Dipòsit Digital de Documents de la UAB 3 registres trobats  La cerca s'ha fet en 0.02 segons. 
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17 p, 2.8 MB Recent advances in the pharmacological targeting of ubiquitin-regulating enzymes in cancer / Montagut, Ana Maria (Universitat Ramon Llull) ; Armengol, Marc Antoni (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; de Pablo, German Gorjón (Universitat Ramon Llull) ; Estrada-Tejedor, Roger (Universitat Ramon Llull) ; Borrell, José Ignacio (Universitat Ramon Llull) ; Roué, Gaël (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
As a post-translational modification that has pivotal roles in protein degradation, ubiquitination ensures that intracellular proteins act in a precise spatial and temporal manner to regulate diversified cellular processes. [...]
2022 - 10.1016/j.semcdb.2022.02.007
Seminars in Cell and Developmental Biology, Vol. 132 (december 2022) , p. 213-229  
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11 p, 2.8 MB Revealing cell vulnerability in Alzheimer's disease by single-cell transcriptomics / Saura Antolín, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Deprada, Angel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Capilla-López, Maria Dolores (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Parra-Damas, Arnaldo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas)
Alzheimer's disease (AD) is a neurodegenerative disorder that by affecting specific brain cell types and regions cause severe pathological and functional changes in memory neural circuits. A comprehensive knowledge of the pathogenic mechanisms underlying AD requires a deeper understanding of the cell-specific pathological responses through integrative molecular analyses. [...]
2022 - 10.1016/j.semcdb.2022.05.007
Seminars in Cell and Developmental Biology, 2022  
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7 p, 1.8 MB A matter of wrapper : Defects in the nuclear envelope of lagging and bridging chromatin threatens genome integrity / Rodriguez-Muñoz, Marina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Anglada Pons, Teresa (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Genescà, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The nuclear envelope surrounds the eukaryotic genome and, through the nuclear pore complexes, regulates transport in and out of the nucleus. Correct nucleo-cytoplasm compartmentations are essential for nuclear functions such as DNA replication or repair. [...]
2022 - 10.1016/j.semcdb.2021.03.004
Seminars in Cell and Developmental Biology, Vol. 123 (March 2022) , p. 124-130  

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